Observations suggesting bioactive Fgf15 is not present in mouse blood
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چکیده
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Observations suggesting bioactive Fgf15 is not present in mouse blood
I read with interest the paper by Uriarte et al, in which the authors conclude that ‘Fgf15 is a key mediator of the liver growth-promoting effects of bile acids.’ There are reasons to question the conclusions drawn in this paper. Due to space limit I forward three issues. (1) Fgf15 exerts its effects via FGFR4 as mentioned. The authors have not recognised a report by Yu et al showing that delet...
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ژورنال
عنوان ژورنال: Gut
سال: 2013
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2013-305227